Identifying greener solvents for square wave voltammetry applications in functional food analysis

Electrochemical methods, specifically square wave voltammetry (SWV) offer fast, portable, and quantitative screening for antioxidant levels lipid degradation in consumer products. Initial studies within our research group utilized benzene as the non-polar component solvent systems analysis. In order to explore additional applications of SWV, less hazardous that maintain or improve on previous figures merit analytes interest are necessary. To this extent, ethanol was selected polar under 7th principle green chemistry (use renewable feedstocks). replace species (benzene), four candidates were identified 5th (safer solvents auxiliaries) including diethyl ether, acetonitrile, isopropyl alcohol, ethyl acetate. Each investigated its own, then varying combinations v/v ratios with ethanol. combination used investigate limit detection, lower quantitation, sensitivity, linearity previously studied antioxidants butylated hydroxytoluene, sesamol, rosemary extract. found yield improved depending tested. After comparing all merit, it 50%–50% ethanol—acetonitrile ethanol—ethyl acetate top five tested, providing a more alternative systems.